11 results
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Secondary to sustained immune ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... be CD4+ but this ... hemepath #pathology #diagnosis
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can ... be community-acquired
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Diagnosis Framework ... Disease by CD4 ... Count: Any CD4 ... Seasonal influenza CD4 ... Blastomycosis CD4
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... occur when the CD4 ... until immune recovery ... (CD4-cell count ... Lymphoma: • CD4
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Purtilo (XLP) Acquired ... Others: Cellular immune
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... cell enzymes - Acquired ... hemolytic anemia, PNH, immune ... • Pneumocystis pneumonia
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... occur at any CD4 ... an increase in CD4 ... Depends On: • CD4
Amebiasis - Balamuthia mandrillaris Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans
trophozoites) can ... with compromised immune ... mandrillaris #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
urinary catheter and immune ... Pathophysiology: ... Coli, but can also ... clostridium, klebsiella pneumoniae ... pyelonephritis CMC
Amebiasis - Acanthamoeba Life Cycle
1) Cysts
2) Trophozoite
3) Mitosis
4) Amebae (cysts and trophozoites) can enter humans in
trophozoites) can ... with compromised immune ... Acanthamoeba #LifeCycle #diagnosis ... #pathophysiology ... infectiousdiseases #cdc