11 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can ... be community-acquired ... x 1 - Adjunct Tx
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... Disease by CD4 ... Count: Any CD4 ... Seasonal influenza CD4 ... Blastomycosis CD4
Community Acquired Pneumonia - Severity and Prognosis
Criteria for Severe CAP - Severe CAP present in 1
Community Acquired ... in 1 major criterion ... criteria: Septic shock ... responsive to IV ... #severe #psi #diagnosis
Community Acquired Pneumonia - Presenting Features
 • History in favor of CAP: Dyspnea, Cough, particularly if
Community Acquired ... Pneumonia - Presenting ... in 1 major criterion ... responsive to IV ... #Pneumonia #diagnosis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
during transient CD4 ... manifestations Labs: • CD4 ... -1 and HIV-2 • ... progression by slowing CD4 ... #HIV #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... occur at any CD4 ... an increase in CD4 ... Depends On: • CD4
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... -> 40 years • Can ... severe community-acquired ... infections: Pneumonia
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... proliferation • ARVs can ... Diagnosis: MRI ... The clinical syndrome ... and with low CD4
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... cause TYPE IV RTA ... /aggregate) of CD4 ... Usual interstitial pneumonia
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... immunodeficiency virus (HIV ... the underlying pathophysiology ... ventilation is required ... Guillain #Barre #Syndrome