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management hemophagocytic hlh lymphohistiocytosis treatment 1 cdiff clostridioides clostridium difficile gastroenterology hematology hemeonc idsa infection infectiousdiseases sjogrens summary syndrome
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Difficile Infection (CDI ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can ... be community-acquired
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Auto-amplification loop Diagnosis ... Purtilo (XLP) Acquired ... treatment #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
5-6th Decades (can ... /aggregate) of CD4 ... Lymphocytic interstitial pneumonia ... Usual interstitial pneumonia ... Sjogrens #Syndrome #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
is a critical diagnostic ... • Secondary (Acquired ... Pathophysiology ... of NK cells and CD8 ... #Management #Hematology
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