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management rheumatology syndrome 1 aids antibiotics associated azithromycin cdiff clarithromycin clostridioides clostridium cystitis dementia differential difficile disorder emphysematous erythromycin gastroenterology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Difficile Infection (CDI ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can ... be community-acquired
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... occur at any CD4 ... an increase in CD4 ... Depends On: • CD4
Emphysematous Cystitis Epidemiology: • Usually middle-aged diabetic women • Other RF: neurogenic bladder, urinary tract outlet obstruction,
Pathophysiology: ... Coli, but can also ... clostridium, klebsiella pneumoniae ... data • Early treatment ... pyelonephritis CMC
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview 50S Ribosomal Inhibitor (PO and IV) Spectrum: Atypical organisms
exacerbations, community-acquired ... pneumonia, sinusitis ... Ceftriaxone for CAP ... Used for MAC treatment ... patients with CD4
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... Diagnosis: MRI ... HIV and with low CD4 ... Treatment: • HAART ... treatment • Cognitive
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
5-6th Decades (can ... /aggregate) of CD4 ... Lymphocytic interstitial pneumonia ... Usual interstitial pneumonia ... Adenocarcinoma Treatment
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