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hematology hemophagocytic hlh lymphohistiocytosis summary treatment 1 antibiotics blastomyces blastomycosis cap cdiff clostridioides clostridium common coverage cvid difficile fungal gastroenterology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Management - GrepMed ... Toxic Megacolon, Shock ... Perforation) Pathophysiology ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock
Antibiotics for severe community-onset pneumonia Atypical coverage always - Usually azithromycin 500 mg daily - Doxycycline
pneumonia Atypical ... piperacillin-tazobactam Septic Shock ... only in selected cases ... #Acquired #Pneumonia ... Antibiotics #Coverage #Management
Blastomycosis (Blastomyces): Gilchrist’s disease, Chicago disease - Summary Sheet • Morphology • Geography, Reservoir and Mode
- Sporadic cases ... blastomycosis – resembles community-acquired ... pneumonia with ... • Management ... #management #summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... #management #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
frequent and severe community-acquired ... infections: Pneumonia ... and M panel Management ... DDX - Other causes ... #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... • Secondary (Acquired ... Pathophysiology ... of NK cells and CD8
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