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management infectiousdiseases 1 capnocytophaga cdiff clostridioides clostridium difficile gastroenterology hemophagocytic hlh idsa infection lymphohistiocytosis microbiology rheumatology summary zoonotic
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... can be community-acquired ... Ileus, Megacolon, Shock ... Treatment Guideline
Capnocytophaga Pathogen: Capnocytophaga • 9 species, C. canimorsus responsible for the majority of infections • Gram-negative rod,
9 species, C. canimorsus ... malaise • Septic shock ... Multiorgan failure: CID ... Meningitis (13%), Pneumonia ... Treatment: • 50%
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Purtilo (XLP) Acquired ... Unknown cause Treatment ... #management #treatment
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