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management syndrome hepatology neurology cirrhosis dermatology differential gastroenterology hemophagocytic hlh lymphohistiocytosis rheumatology summary symptoms adhd algorithm als amyotrophic antinxp2 antinxp2dm
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary Diagnostic ... erythropoietin 1/ ... present, symptoms, signs ... with evidence of acquired ... #hematology
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Management Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #Management #dermatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
* Bloating not required ... for diagnosis Treatment ... Rifaximin- up to 3 courses ... Gastroenterology and Hepatology ... gastroenterology #treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Perforation) Pathophysiology ... Epidemiology: • #1 ... can be community-acquired ... 10 mg/kg IV x 1
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Purtilo (XLP) Acquired ... Treatment: • ... #management #treatment ... #summary #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... dysfunction (16%) • Shock ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Female:Male 9:1 ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... • AMA titer 1:
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
other obvious causes ... thromboembolism) 1) ... m/s • Other signs ... pressure < 15mmHg TREATMENT ... Effect: PATENT-1
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