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management hepatology syndrome arteritis biliary cholangitis coagulation dic disseminated gca giantcell hemophagocytic hepatopulmonary hlh hps intravascular leukostasis lymphohistiocytosis lysis pbc
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... #workup #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Purtilo (XLP) Acquired ... Treatment: • ... #management #treatment ... #summary #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... dysfunction (16%) • Shock ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... arteriovenous shunting causes ... • Stigmata of cirrhosis ... the left heart TREATMENT ... #diagnosis #hepatology
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