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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... Toxic Megacolon, Shock ... can be community-acquired ... 10 mg/kg IV x 1 ... #treatment #infectiousdiseases
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Stages: 1. ... host response to infection ... pneumothorax, cardiac ... Types #diagnosis #management ... warm #wet #dry #table
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Skin exam for infection ... exam Determine Cardiac ... > 1% risk of CV ... Change in clinical ... medical and surgical management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
risk secondary ... • Affects 1:25,000 ... and 1:50,000 patients ... to 8 years Clinical ... severe community-acquired
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
the majority of infections ... Incubation period is 1- ... malaise • Septic shock ... microbiology #zoonotic #infectiousdiseases ... #diagnosis #management
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary 1. ... Pts: cardiogenic shock ... and timing with Cardio-OB ... Delivery • Stable ... months before 1°
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Diagnosis and Management ... • Severe: Only 1% ... useful for chronic infection ... evidence of cardiac ... #Microbiology #InfectiousDiseases
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Food products Risk ... /Other RGM • Cardiac ... Complex (MAC): • Acquired ... patients such as: 1. ... differential #diagnosis #infectiousdiseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk ... forms: 1) Rhinocerebral ... fever • Septic shock ... ) #Mycoses #InfectiousDiseases ... Fungal #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... MANIFESTATIONS: • The cardinal ... specific therapy, the clinician ... ventilation is required ... Syndrome #diagnosis #management