4 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Acute DIC - Septic shock ... Deficiencies #Summary #table ... comparison #diagnosis #hematology ... #deficiency
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Purtilo (XLP) Acquired ... Cellular immune deficiency ... Lymphohistiocytosis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... dysfunction (16%) • Shock ... thrombopoietin deficiency ... causes #treatment #management ... #hematology
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
heart (Sepsis, Shock ... are typically able ... algorithm #cardiology #echocardiogram ... #management #clinical