4 results
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... post-ABx, but can be community-acquired ... Ileus, Megacolon, Shock ... despite appropriate treatment ... IDSA 2021 CDI Treatment
CSF Penetration of Antimicrobials

Despite the poor CSF penetration, beta-lactams have the most research documenting successful treatment
Penetration of Antimicrobials ... documenting successful treatment ... of community-acquired ... FDA-approved for UTI treatment ... Penetration #CNS #Antimicrobials
Macrolides - Erythromycin, Clarithromycin, Azithromycin - Antibiotics Class Overview

50S Ribosomal Inhibitor (PO and IV)
Spectrum: Atypical organisms
exacerbations, community-acquired ... Used for MAC treatment ... #Antibiotics #Review
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
choice, both for treatment ... prophylaxis), Community-acquired ... #Antibiotics #Review