16 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) ... Guidelines ACLF ... months without treatment ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute Liver ... HSV • Toxic: Alcohol ... Hepatic Artery: Shock ... Medication, Pregnancy, Alcoholic ... Acute #algorithm #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... ) • Advanced Liver ... Disease - Alcohol ... Acute DIC - Septic shock ... comparison #diagnosis #hematology
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... can be bridge to Liver ... Niriella @madunil #Alcoholic ... Management #Algorithm #treatment ... #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
patients), "Hospital-acquired ... Non-megaloblastic: Alcohol ... use, Liver disease ... independent of alcohol ... diagnosis #causes #hematology
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Nosocomial or hospital acquired ... Presentation in septic shock ... dysfunction or liver ... Diagnosis #Management #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... liver disease, ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Hepatic artery: Shock ... VZV • Trauma: Shock ... ALT Ratios: • Alcoholic ... diagnosis #algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
for HIV, HCV - Alcohol ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... evaluation: not required ... Causes #Workup #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Failure (ALF): ... • Liver injury ... ALT Ratios: • Alcoholic ... #differential #Hepatology