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diagnosis liver algorithm differential hepatitis management acute chemistry cirrhosis dili druginduced failure gastroenterology interpretation lfts rvalue transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... Diagnosis #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Hepatic artery: Shock ... VZV • Trauma: Shock ... ALT Ratios: • Alcoholic ... : > 3 • Chronic ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure (ALF ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... : > 3 • Chronic ... #differential #Hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Acute kidney injury ... Multiorgan failure or shock ... prednisolone #Alcoholic ... Management #Algorithm #hepatology
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