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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Clostridioides Difficile Infection ... on ABx) → Acute ... #1 nosocomial infection ... IDSA 2021 CDI ... #Clostridium #Infection
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... immunodeficiency virus infection ... • >50,000 HIV infections ... within 28 days of infection ... /early infection
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Disseminated Infections ... 50% in chronic infection ... infection MUCORMYCOSIS ... River valleys • Infection ... fever • Septic shock
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
IDSA Recommendations ... Anti-motility agents can ... Gastrointestinal Infections ... available for this infection ... opportunistic #infections
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
(GBS) Acute autoimmune ... to a preceding infection ... • Most common infection ... jejuni • Other infections ... and cauda equina TREATMENT
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... surface molecules: CD5 ... microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute ... Inhibitors of Na+CI ... myocardial infarction ... • Hypovolemic shock ... Tolvaptan) • Treatment
IDSA - Approach to Treating a Patient With Diabetic Foot Osteomyelitis
When to consider a trial of
IDSA - Approach ... for C. difficile infection ... adjacent soft tissue infection ... Persistent sepsis syndrome ... Osteomyelitis #Infection