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management diagnosis infectiousdiseases rheumatology candida cdi cdiff clostridioides clostridium difficile esophageal fungal gastroenterology hematology hemophagocytic hivaids hlh infection lymphohistiocytosis macrophage
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days) Preferred
IDSA Recommendations ... 4–6 mL QID or 1– ... antifungals are required ... candida #mucosal #IDSA ... opportunistic #infections
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... Purtilo (XLP) Acquired ... Histoplasmosis, candidiasis ... Unknown cause Treatment
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... can be community-acquired ... Ileus, Megacolon, Shock ... 10 mg/kg IV x 1
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... the secondary or acquired ... cytokines, such as IL-1 ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
clinical forms: 1) ... Fluconazole SYSTEMIC CANDIDIASIS ... fever • Septic shock ... blood cultures Candidiasis ... colonization Candidiasis
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