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Clostridium Difficile Diagnosis and Management Algorithm

IDAGRAM based on most recent guidelines from @IDSAInfo.

 Infographic by IDagram
@ID_agram

#Clostridium
Clostridium Difficile Diagnosis ... Difficile #Algorithm #Treatment ... #Diagnosis #Management ... #IDSA #CDiff
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Toxic Megacolon, Shock ... can be community-acquired ... Tx Management (IDSA ... Ileus, Megacolon, Shock ... ciab549 #CDI #Cdiff
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
IDSA Recommendations ... antifungals are required ... for effective treatment ... candida #mucosal #IDSA ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Preventing Human Papillomavirus Infections and Cervical Cancer Screening for Women with in HIV-AIDS
Recommendations
IDSA Recommendations ... or been newly diagnosed ... following initial diagnosis ... #Prevention #Treatment ... opportunistic #infections #HIVAIDS
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Framework Diagnosis ... Immunocompromise Treatment ... • Secondary to Treatment ... Secondary infection (C diff ... ) • Hospital-Acquired
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS
Preventing Chronic Microsporidiosis:
 • Because chronic microsporidiosis occurs
IDSA Recommendations ... : • The best treatment ... Microsporidiosis #IDSA ... #Prevention #Treatment ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS
Pre-Exposure Prevention of VZV
IDSA Recommendations ... health-care provider diagnosis ... vaccine virus, treatment ... #Zoster #VZV #IDSA ... opportunistic #infections #HIVAIDS
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... prior history of treatment ... and molecular diagnostic ... Tuberculosis #TB #IDSA ... opportunistic #infections #HIVAIDS
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Diagnosis? ... EMD myeloma Diagnostic ... • CBC + diff • ... Bone marrow Treatment ... chemotherapy as required