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diagnosis differential arthritis management erythematosus lupus patterns ra systemic vasculitis autoantibodies autoimmune classification disease fungal infections infectiousdiseases laboratory mimickers monoarthritis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Rheumatoid arthritis ... characteristic antibodies ... Peptide (aCCP), Rheumatoid ... Extra-articular signs ... #symptoms #diagnosis
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... knees, shoulders Signs ... & Symptoms: • ... history, exam and ... diagnosis #management #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... ) - Antinuclear ... antibodies, which ... diagnosis #testing #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... - Autoimmune Rheumatologic ... arthritis • SLE ... Symmetrical: • RA • SLE
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Auto-Antibodies ... : - ANA 95-100% ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
- Signs and Symptoms ... Musculoskeletal: Joint ... Arthritis #RA #Signs ... #Symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Diagnosis: Systemic rheumatic ... purpura: strong sign ... ) pattern: antibodies ... SLE) • Urinalysis
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