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diagnosis differential erythematosus lupus neurology syndrome systemic vasculitis antinuclear arthritis autoantibodies behcet classification fungal gravis hematology hemeonc hemophagocytic hlh infections
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... Rheumatic Diseases ... • Rheumatic Diseases ... #rheumatology #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Auto-Antibodies ... : - ANA 95-100% ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... arthritis • SLE ... Differential #Diagnosis #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Sjogren syndrome, rheumatoid ... arthritis, SLE ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... • Arthritis: SLE ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic rheumatic ... Presentation - Systemic Symptoms ... purpura: strong sign ... ) pattern: antibodies ... SLE) • Urinalysis
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Management Summary ... • Rheumatoid ... anti-citrullinated peptide antibodies ... PMR #Diagnosis #Management ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... hypofunction • Antibodies ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Management • ... caucasian • Symptoms ... Unilateral • Signs ... other auto-immune diseases ... #treatment #rheumatology
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