20 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Mechanical/degenerative disorders ... noninflammatory Signs ... constitutional symptoms ... - Autoimmune Rheumatologic ... Diagnosis #MSK #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Summary Overview: chronic ... knees, shoulders Signs ... & Symptoms: • ... inflammatory) • joint pain ... diagnosis #management #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... in persons with rheumatoid ... : • Acute or chronic ... #MSK #rheumatology ... #approach #workup
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... • Rheumatic Diseases ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and duration of symptoms ... Nausea, abdominal pain ... , Hypotension, shock ... Atopic diseases, Chronic ... Urticaria #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Chronic ... metabolic or endocrine disorders ... , and low back pain ... diagnosis #testing #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... lymphoproliferative disorders ... Leukemia #diagnosis #workup ... #oncology #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
syndrome is a rare chronic ... inflammatory disorder ... Autoinflammatory disorder ... skin lesions + Rheumatic ... SAPHO #Syndrome #Rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... bacterial), acute rheumatic ... fever • Chronic ... #rheumatology # ... approach #workup