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diagnosis hematology management oncology leukemia lupus algorithm behcet cancer comparison differential disease druginduced erythematosus essential et hemeonc hemophagocytic hlh lymphocytic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... develop leukostasis syndrome ... • Tumor lysis syndrome ... ) CLL Symptoms:
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... Leukemia #diagnosis #workup
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... Constitutional symptoms ... • Treatment: ... • Evolution: Chronic ... comparison #table #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... Arthritis, AS Treatment ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... (C3 and C4) • ds-DNA ... with Lupus: • Chronic ... Erythematosus #Diagnosis #Rheumatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... When present, symptoms ... PV, MDS, CML) Treatment ... transformation into MDS ... or AML
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... disease-associated symptoms ... with repeated red cell
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
with the HLH syndrome ... (often termed MAS-HLH ... Presentation • Common Signs ... and Symptoms: ... Diagnosis #Management #Hematology
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