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diagnosis amiodarone differentiation hematology lung oncology pulmonary syndrome toxicity
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... endothelial damage • Induce ... Differential Diagnosis: Infection ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
toxicity (e.g., acute ... Pleuritic chest pain ... failure - Infectious ... Pulmonary #diagnosis #management ... #Toxicology
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