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diagnosis differential hepatology dermatology injury systemic generalized pruritus bileduct biliary dilatation dilated drug druginduced hepatitis idiosyncratic induced management naildisorders primary
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
presentation • Chronic ... or symptoms of liver ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ischaemia ... e.g. ascites), Chronic ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #hepatology
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... Inflammatory: Chronic ... pancreatitis, PSC (or secondary ... Parasitic infection, Ischaemic ... #gastroenterology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Systemic and Primary Causes ... Creatinine & BUN: • Chronic ... Pruritus #primary #secondary ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Liver ... discoloration) • Chronic ... #Diagnosis #Algorithm ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
• Cholestatic liver ... Creatinine & BUN: • Chronic ... #Pruritus #secondary ... #generalized #dermatology ... #causes
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