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diagnosis dermatology differential systemic generalized management alkaline alp cellulitis common cryofibrinogenemia cvid hemeonc hemophagocytic hepatology hlh hyophosphatasia hypogammaglobulinemia immunodeficiency immunology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... renal failure/uremia ... #primary #secondary ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology ... #causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... discoloration) • Liver ... #Diagnosis #Algorithm ... #causes
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... sepsis: chronic liver ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... #legs #clinical
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
• Painful or pruritic ... limb and bowel ischemia ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... synthesized in: liver ... pain • loss of secondary ... • Pernicious anemia ... Phosphatase: • Other causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... disease • Liver ... autoimmune hemolytic anemia ... DDX - Other causes
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... STX11, STXBP2 • Secondary ... Clinical Presentation ... - Cytopenias (anemia ... - Elevated liver
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