14 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Algorithm - Systemic ... and Primary Causes ... • Cholestatic liver ... renal failure/uremia ... #Algorithm #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... ischemia and/or ... #management #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... , - regional ischemia ... of lactate as a clinical ... of Circulatory System ... 30mmHg) - Severe anemia
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Algorithm Blood ... renal failure/uremia ... Pruritus #secondary #systemic ... #generalized #dermatology ... #Algorithm #causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... disease • Liver ... autoimmune hemolytic anemia ... DDX - Other causes ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... with leukopenia, anemia ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... complaints- anemia ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... #Management
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
Systemic causes ... include diabetes, anemia ... hyperthyroidism, peripheral ischemia ... Seen in liver disease ... Abnormal #Pathology #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... #Diagnosis #Management