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diagnosis differential injury lfts transaminitis aclf ascites chemistry chronic druginduced failure function gastroenterology gradient hepatorenal hrs interpretation management nephrology rvalue
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... (>1000): • DILI ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Circulation Failure Kidney ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... disease, Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... : < 1 • Cirrhosis ... differential #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Production: • Albumin ... : < 1 • Cirrhosis ... #differential #Hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
- Alcoholic hepatitis ... Veno-occlusive disease - Acute ... fatty liver of ... associated with bowel ischemia ... Differential #Diagnosis #hepatology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
disease: cirrhosis ... severe alcoholic hepatitis ... , or acute liver ... - IV albumin ... Hepatorenal #Syndrome #Hepatology
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