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diagnosis differential injury causes aih lfts coagulation comparison deficiencies dehydrogenase dili druginduced elevated hematology laboratory lactate ldh liverenzymes liverinjury management
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... - Autoimmune ... -1 antitrypsin deficiency ... #Differential #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... Celiac Disease Hepatocellular ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
alternative causes • Hepatocellular ... disease, Hepatic ischaemia ... dechallenge • Acute ... steatosis • Autoimmune ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Autoimmune ... • AIH • A1AT deficiency ... • Alcoholic hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... Acute Liver Injury ... : Autoimmune hepatitis ... #hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Alcohol, Viral hepatitis ... , Autoimmune • ... Post-partum • Acute ... catastrophes, Acute
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... factors - Possible ischemic ... ) or metabolic liver ... 1 antitrypsin deficiency ... #Hepatology #AIH
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
RBCs, muscle, liver ... Injury: • Early acute ... hepatitis • Ischemic ... hepatitis • Acute ... Hepatocellular
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... subclinical disease to acute ... liver failure ... - Typically hepatocellular ... Diagnosis #Management #Hepatology
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