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diagnosis differential injury liver lfts acute dili druginduced gap globulin hearingloss hematology hepatocellular hepatomegaly liverenzymes protein proteingap sensorineural transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Autoimmune ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... #Causes
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Inflammatory • Alcoholic ... Hepatitis • Autoimmune ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Schistosomiasis - Autoimmune ... Sarcoidosis Toxic - Alcohol ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Other: NAFLD, Autoimmune ... #Acute #algorithm ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... steatosis • Autoimmune ... #hepatology
Sensorineural Hearing Loss - Differential Diagnosis Algorithm Asymmetric Sensorineural Hearing Loss: • Neoplastic (Vestibular Schwannoma) •
HIV, Syphilis, Hepatitis ... Teratogenic drugs, Alcohol ... Cardiovascular Ischemia ... Meniere's Disease • Autoimmune ... #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... : Autoimmune hepatitis ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Liver disease: Cirrhosis ... , ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis
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