15 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... vs Hypocellular MDS ... Expectation • Rx Algorithm ... Anemia #diagnosis #oncology ... #hematololgy
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Non-hemolytic: ACD, Aplastic ... Liver disease, Alcoholism ... Reticulocytosis, MDS ... Differential #Diagnosis #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Drugs/Toxins • Ischemia ... • NAFLD • Alcohol ... • AIH • A1AT deficiency ... hepatitis • Drugs ... Others #LFTs #Hepatology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
• 812, Folate Deficiency ... • MDS+ • Hypothyroid ... Liver Disease • Alcohol ... differential #diagnosis #algorithm ... #hematology #workup
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Hepatitis (AH) ... factors • Possible ischemic ... hepatitis (e.g. ... I antitrypsin deficiency ... #hepatology #criteria
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... assessed not only by MDF ... #Algorithm #treatment ... #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... Anemia: - Hepatitis ... #Anemia #oncology ... #hematology #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
HSV • Toxic: Alcohol ... Medication, Pregnancy, Alcoholic ... - Sophia Hayes MD ... Causes #Acute #algorithm ... #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... factors - Possible ischemic ... hepatitis (e.g. ... 1 antitrypsin deficiency ... #Diagnosis #Hepatology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... Alcoholism Bone ... FISH • Acquired Aplastic ... • Hypoplastic MDS ... #Hematology