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diagnosis differential liver injury management alcoholic druginduced elevated fatty lfts liverenzymes obgyn obstetrics pathophysiology pregnancy transaminases transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ischaemia ... disorder (e.g. ascites ... #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
• Autoimmune hepatitis ... • Iatrogenic: DILI ... See Updated Schema ... Differential #Diagnosis #causes ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Pregnancy - AFLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... develops (DIC, ascites ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... • Iatrogenic: DILI ... differential #diagnosis #algorithm ... #hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... blood, urine and ascites ... HCV, DILI, HCC, ... #hepatology
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