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diagnosis differential lfts transaminitis injury abnormal acute ascites chemistry dili druginduced fatigue function gap globulin hematology hepatitisb hepatocellular hepatomegaly iga
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... normal - Infection (EBV ... cirrhosis, Portal ... 5-10x normal - Chronic ... #Injury #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... viremia or have cirrhosis ... Chronic Hepatitis ... #HepatitisB #HBV ... Management #Treatment #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... Trauma: Shock liver ... See Updated Schema ... Differential #Diagnosis #causes ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... EBV, CMV), Alcohol-related ... Hepatic ischaemia ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... Infiltrative • Cirrhosis ... #Causes
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... • NAFLD • Cirrhosis ... • Chronic Viral ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... heart failure (chronic ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Vascular Causes ... , HBV, HCV, HEV, ... specificity to elevated ... : < 1 • Cirrhosis ... #hepatology
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