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differential causes injury lfts transaminitis ascites hematology management acute aclf albumin chemistry common cvid diffuse dili disease druginduced elevated epidemiology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... Chronic Hepatitis ... #HepatitisB #HBV ... #Algorithm #Diagnosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Hepatitis > ... CMV), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Injury #hepatology ... #differential #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... Hepatic ischaemia ... hepatitis fibrosis ... • Autoimmune hepatitis ... #Algorithm #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... • Autoimmune hepatitis ... See Updated Schema ... Transaminases #hepatitis ... #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... • Chronic Viral ... Hepatitis Moderate ... • Acute Viral Hepatitis ... injury) • Ischemic
Hepatitis B Disease Progression Timeline • > 90% of infected children progress to chronic disease (<5%
Hepatitis B Disease ... develop Liver Cancer ... develop cirrhosis ... #HepatitisB #Disease ... Timeline #Prognosis #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
- Differential Diagnosis ... Chronic liver disease ... (cirrhosis or chronic ... hepatitis) - 80% ... #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Nonalcoholic fatty liver ... heart failure (chronic ... 14 percent) #Diagnosis
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 Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Infectious • Hepatitis ... • Alcoholic Hepatitis ... • Autoimmune Hepatitis ... • Drug Induced Hepatitis ... #Hepatology
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