8 results
diagnosis differential causes injury lfts transaminitis acidosis chemistry classification dehydrogenase druginduced elevation hepatocellular interpretation laboratory lactic ldh liverenzymes rvalue transaminases
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... Trauma: Shock liver ... • Iatrogenic: DILI ... See Updated Schema ... Diagnosis #causes #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... Hepatic ischaemia ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, HBV, HCV, HEV, ... • Iatrogenic: DILI ... specificity to elevated ... ALT Ratios: • Alcoholic ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • NAFLD • Alcohol ... hepatitis • Drugs ... Others #LFTs #Hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... RBCs, muscle, liver ... • Ischemic hepatitis ... fever) • Drugs (alcohol ... disease #LDH #Lactate
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... serologies, HCV ... specificity to elevated ... ALT Ratios: • Alcoholic ... #differential #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
, - regional ischemia ... Causes of elevated ... 30mmHg) - Severe anemia ... Hypoglycemia - Alcohol ... Ethylene glycol - HIV
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