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diagnosis differential injury lfts transaminitis ascites management saag aflp albumin chemistry chronic cirrhosis dermatology diffuse dili druginduced elevated fatigue globulin
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 20x normal - Acute ... normal - Infection (EBV ... /CMV), Alcoholic ... #Injury #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... EBV, CMV), Alcohol-related ... Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #Acute #algorithm ... #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... • Autoimmune hepatitis ... See Updated Schema ... Differential #Diagnosis #causes ... #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... - Drug-Induced liver ... #Hepatology #Diagnosis
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty ... Liver • Cysts ... Inflammatory • Alcoholic ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Sarcoidosis Toxic - Alcohol ... - Nonalcoholic fatty ... liver disease ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... = nonspecific (nausea ... , ↑Tbili/Dbili/AP ... Diagnosis: Viral Hepatitis ... #hepatology #obstetrics
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes ... of Acute Liver ... , HBV, HCV, HEV, ... #hepatology
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