7 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Wilson's, HH, NAFLD ... kwburak #LFTs #Elevated ... #hepatology #LiverFunctionTests
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... 100-500): • NAFLD ... (Drug-induced liver ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... ALT < 5x ULN • NAFLD ... disease US — Normal ... Others #LFTs #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... • Vascular: Ischemic ... antitrypsin • Other: NAFLD ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... specificity to elevated ... function may be abnormal ... #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
RBCs, muscle, liver ... upon damage • Normal ... Hepatocellular Injury ... • Demand ischemia ... differential #diagnosis #Laboratory
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
injury, though ... IgG typically elevated ... upper limit of normal ... Necrosis) If mild laboratory ... Diagnosis #Management #Hepatology