8 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
- Ischemic Hepatitis ... - Acute Viral Hepatitis ... AST:ALT = 1 - Ischemia ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Drugs/Toxins • Ischemia ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Differential Diagnosis Algorithm ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... limb ischemia, ... organ damage • Treatment ... diagnosis #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
levels - Usually normal ... decrease in most cases ... tissue damage from ischemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
Acute Pancreatitis ... Familial, Infectious, Ischemia ... Imaging findings Workup ... Lipase, Ca2+, LFTs ... Diagnosis #Management #Treatment
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... Better call hematology ... phlebotomy, or chemo ... #workup #hematology