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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
Acute Pancreatitis ... Familial, Infectious, Ischemia ... Lipase, Ca2+, LFTs ... #Diagnosis #Management ... #Treatment #Gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... limb ischemia, ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... #diagnosis #management ... #hepatology #gastroenterology
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
the setting of acute ... cannot, coronary ischemia ... #diagnosis #algorithm ... echocardiogram #management ... criticalcare #foamed #treatment