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hematology management cell chronic classification color differentiation essential et hodgkins leukemia lymphocytic lymphoma maculopapular mds myelodysplasia myelodysplastic plasmacytoma rash scaling
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Algorithm Pathophysiology ... sulfa-drug - Skin pain ... #Differential # ... Ddxof
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
atypical chest pain ... PV, MDS, CML) Treatment ... transformation into MDS or AML ... • Treatment algorithms ... #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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