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diagnosis causes coagulation management symptoms hepatology prolonged pt algorithm arteritis biliary centralretinalartery cholangitis cirrhosis comparison crao dic disseminated enzymes gca
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... Causes #diagnosis #differential ... #hematology #coagulation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... symptoms/signs ... #Algorithm #Hepatology ... #Differential #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... DIC • Severe Liver ... INR < 2.3 - APTT ... treatment #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... the spleen or liver ... also arise in normal ... involvement Differential ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... failure PBC Signs ... or higher • Liver ... bile ducts Differential
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... congenital defects) -> Abnormal ... anti-coagulation • Hematologic ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... 50 in GCA, but normal ... GCA #Temporal #Signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... heart (2-5%), liver ... (pain/abnormal ... Diagnosis #Management #Signs
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