15 results
diagnosis hepatology causes management coagulation symptoms algorithm comparison lfts prolonged pt workup aflp arteritis biliary centralretinalartery cholangitis cirrhosis crao dic
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Drugs/Toxins • Ischemia ... disease US — Normal ... Others #LFTs #Hepatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... Causes #diagnosis #differential ... #hematology #coagulation
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... symptoms/signs ... the magnitude of enzyme ... #Liver #Enzymes ... #Differential #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
weeks • Typical clinical ... Hepatic imaging: Normal ... enzymes, and Low ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... DIC • Severe Liver ... INR < 2.3 - APTT ... treatment #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... the spleen or liver ... also arise in normal ... involvement Differential ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
value for this enzyme ... performed PT, PTT ... tissue damage from ischemia ... WBC count and differential ... Diagnosis #Workup #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... cholestasis → Cirrhosis/Liver ... failure PBC Signs ... or higher • Liver ... bile ducts Differential
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Pathogenesis and clinical ... congenital defects) -> Abnormal ... anti-coagulation • Hematologic ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
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