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diagnosis management causes hepatology rheumatology coagulation neurology syndrome algorithm dermatology gca infections neck ophthalmology photo poikiloderma prolonged pt rash workup
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... cases: INR/PT, aPTT ... (liver disease, ... pylori test (GI symptoms ... bypass), LFT (liver
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... initial response to abnormal ... symptoms/signs ... #Algorithm #Hepatology ... #Differential #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... the spleen or liver ... also arise in normal ... involvement Differential ... #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Maternal Support - Critical ... #Pregnancy #hepatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Anterior ischemic ... Definition: acute ischemic ... Clinical manifestations ... Doppler US : halo sign ... efficacy of GCs Abnormal
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... AKI, acute limb ischemia ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... DIC • Severe Liver ... INR < 2.3 - APTT ... treatment #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... or higher • Liver ... bile ducts Differential
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