16 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... APS), Secondary ... CNS #neurology #rheumatology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Pathogenesis and Clinical ... excess secretion of hCG ... Secondary hyperthyroidism ... Signs/Symptoms: ... endocrinology #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... AKI, acute limb ischemia ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
thought to be secondary ... syncope (ruling out differential ... orthostatic vital sign ... and an initial ECG ... should be guided by clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... Cryofibrinogenemia Clinical ... limb and bowel ischemia ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup and Differential ... hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... - (Ischemia, ... Type III Often Secondary ... tissue disorder (e.g ... classification #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... EMG: LMN Signs in ... conditions listed in differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet disease) Differential ... retinal tears, Ischemia ... diagnosis #management #signs ... #symptoms #rheumatology