9 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... that will cause ischemia ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Age Related Macular ... Pathogenesis and clinical ... choroidal bed -> Ischemia ... MacularDegeneration #pathophysiology ... #ophthalmology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... them, but urgent rheumatology ... required +/- prompt ophthalmology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... retinal tears, Ischemia ... inhibitors • Uveitis- Ophthalmology ... signs #symptoms #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... limb and bowel ischemia ... pulmonary emboli, and ocular ... Diagnosis: • + Clinical ... Cryofibrinogenemia #diagnosis #rheumatology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Pathogenesis and Clinical ... intra- or peri-ocular ... nerve head - Ischemic ... OpenAngle #Glaucoma #pathophysiology ... #ophthalmology
Myopia: Pathogenesis and clinical findings

 • Axial length of eye -> Long axial length of the
Pathogenesis and clinical ... of one or more ocular ... of the eye (ex. cataract ... vision #Myopia #pathophysiology ... #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
Pathogenesis and Clinical ... alteration in ECM ... nerve head - Ischemic ... Secondary #Glaucoma #pathophysiology ... #ophthalmology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... , with ensuing ischemia ... has five major clinical ... Aspergillosis Pathophysiology ... osteoarticular, pulmonary, ocular