8 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... • Secondary glaucoma ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
edema caused by ischemia ... axons death due to ischemia ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
from choroid to retina ... choroidal bed -> Ischemia ... early disease) #AgeRelated ... MacularDegeneration #pathophysiology ... #ophthalmology
Isocoria - Pupillary Defects - Differential Diagnosis Algorithm
Relative Afferent Pupil Defect
 • Optic Neuritis
 • Ischemic
Differential Diagnosis Algorithm ... Optic Neuritis • Ischemic ... Nerve Tumor • Retinal ... Midbrain (Parinaud's Syndrome ... #Causes #Ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
causes fluffy white ischemic ... Elschnig's Spots • Ischemia ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
disease (panuveitis, retinal ... meningitis), MCC CNS symptoms ... tears, Ischemia ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
influx and NO in retinal ... nerve head - Ischemic ... > Apoptosis of retinal ... #pathophysiology ... #ophthalmology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... influx and NO in retinal ... nerve head - Ischemic ... #pathophysiology ... #ophthalmology