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hematology management differential hemophagocytic hlh lymphohistiocytosis oncology vasculitis algorithm antiphospholipid apls behcet chronic cll cryofibrinogenemia cryoglobulinemia cryoglobulins dementia disease geriatrics
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
1) Clinical diagnosis ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Unique or multiple ischemic ... #Workup #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... AKI, acute limb ischemia ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... - (Ischemia, ... Labs/Diagnosis: ... #types #classification ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... retinal tears, Ischemia ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... : HLH signs and ... Diagnosis via genetic ... management #treatment #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
limb and bowel ischemia ... : • + Clinical ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... Kidneys: glomerular ischemia ... purpura: strong sign ... #rheumatology # ... classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... -95% of cases) Classification ... Hodgkin Lymphoma Workup ... #classification ... #hematology #oncology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
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