9 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
While the pathophysiology ... flexion occurs as ... despite severe disease ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... disorders, Aseptic Meningitis ... Cerebrovascular Disease ... , PRES Pathophysiology ... (for secondary APS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... lesions, aseptic meningitis ... Medium and large also ... retinal tears, Ischemia ... diagnosis #management #signs
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
Pathogenesis and clinical ... choroidal bed -> Ischemia ... RPE -> Loss of photo ... Asymptomatic (early disease ... MacularDegeneration #pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of the clinical ... lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... 4) progressive muscular
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... narrowing and vascular ... damaged BRB appears as ... #Retinopathy #pathophysiology ... ophthalmology #diagnosis #signs
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
endotoxin induces vascular ... leading to organ ischemia ... that persists as ... Immunization #peds #pediatrics ... #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Pathogenesis and clinical ... Oxidative stress, Ischemia ... disease and neuropathy ... neurovascular disease ... #DiabeticFoot #pathophysiology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
, with ensuing ischemia ... has five major clinical ... fungal stain of clinical ... Aspergillosis Pathophysiology ... : • Meningitis,