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diagnosis differential hematology vasculitis acute arterial classification coronavirus covid19 cryofibrinogenemia diffuse distention embolism extrapulmonary leukostasis lysis management pain sarscov2 signs
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
Differential Diagnostic Algorithm ... musculoskeletal causes ... genitourinary causes ... • Mesenteric ischemia ... • Sickle cell anemia
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Ageusia, Myalgia, Anosmia ... , Stroke • Renal ... Gastrointestinal: Diarrhea, Nausea ... /vomiting, Abdominal ... shock, Myocardial ischemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... tissue damage from ischemia ... Diagnosis #Workup #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Nephrotic Syndrome, Ischemic ... considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Abdominal Distention - Differential Diagnostic Algorithm Ascites Bowel Dilatation Other Causes Mechanical Obstruction • Adhesions 60% • Volvulus 3% •
Abdominal Distention ... Dilatation Other Causes ... Infectious • Ischemic ... Spinal Injury, Stroke ... ) #Abdominal
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... and mesenteric ischemia ... Non-glomerular ischemia ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... tract, and often causes ... Kidneys: glomerular ischemia ... Palpable purpura: strong ... differential #diagnosis #rheumatology
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