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diagnosis differential hematology classification management arterial bone cryofibrinogenemia cryoglobulinemia cryoglobulins embolism joint leukostasis lysis pain pathophysiology prs pulmonary renal sicklecell
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... tract, and often causes ... Kidneys: glomerular ischemia ... Palpable purpura: strong ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: • Purpura, ischemic ... and mesenteric ischemia ... Non-glomerular ischemia ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • Mechanism: ischemic ... Pain #SickleCell #Disease ... #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Myeloproliferative disease ... Nephrotic Syndrome, Ischemic ... coagulation and other causes ... 19 - PNH - Vasculitis ... pathophysiology #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... - (Ischemia, ... classification #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... decrease in most cases ... tissue damage from ischemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... EGPA) • Digital ischemia ... mononeuritis multiplex WORKUP ... Goodpasture's cause
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