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diagnosis management hematology signs differential gca oncology arteritis classification deficiency giantcell nutrition syndrome vasculitis 2ndline aion algorithm anteriorischemicopticneuropathy aplastic b12
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Anterior ischemic ... Is visual loss caused ... Definition: acute ischemic ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... symptoms, coma ... AKI, acute limb ischemia ... diagnosis #management #hematology
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Ageusia, Myalgia, Anosmia ... , Stroke • Renal ... Gastrointestinal: Diarrhea, Nausea ... shock, Myocardial ischemia ... Diagnosis #Signs #Symptoms
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
dental fixatives, Treatment ... Hypercholesterolaemia, Ischaemic ... heart disease, Stroke ... Haematological: Anaemia ... #riskfactors #symptoms
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... mg/kg/day • Ischemic ... scalp necrosis, stroke ... MTX or TCZ in case ... #Indications #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... tissue damage from ischemia ... Diagnosis #Workup #Hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... Heat injury, Heat stroke ... : • Triad of symptoms ... urine • Other symptoms ... perfusion → renal ischemia
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... hypoxia and organ ischemia ... to manifest its symptoms ... , alcohol use, symptoms ... Check for IF ab Treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... Treatment: ... • Improve the symptoms ... #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... #hematology
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