18 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #hepatology #LFTs
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... #Differential # ... Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... • NAFLD • Cirrhosis ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... decreased renal renal ischemia ... Treatment: 1 ... Management #Summary #causes ... #treatment
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
If concern for ischemic ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... : case-by-cased ... management #Algorithm #hepatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
Alzheimer - 1st cause ... Dementia - 2nd cause ... Unique or multiple ischemic ... MNCD #Dementia #Differential ... #Subtypes #Classification
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... Diagnosis #Algorithm #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... , - regional ischemia ... - regional ischemia ... - Mesenteric ischemia ... #typea #typeb #classification
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... perfusion → renal ischemia ... Rhabdomyolysis #Differential ... Diagnosis #Management #causes