74 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... , Ischemic Necrosis ... #Injury #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... #Differential #Hepatology ... #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... • NAFLD • Cirrhosis ... Chronic Viral Hepatitis ... injury) • Ischemic ... #hepatology #transaminitis
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Disease (Cirrhosis ... Complications • Ascites ... • Hepatorenal Syndrom ... #diagnosis #management ... #summary #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Diagnosis Chronic ... liver disease ( ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... #hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... , Massive liver ... albumin #gradient #hepatology ... #differential #diagnosis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
- Differential Diagnosis ... - Alcoholic hepatitis ... - Massive liver ... associated with bowel ischemia ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... of portal HTN: ascites ... Clues to non-cirrhotic ... /acute hepatitis ... #causes #hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential #Hepatology ... #Cirrhosis #Causes
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Decompensation • Ascites ... Scenarios • Alcoholic Hepatitis ... • Hepatorenal Syndrome ... Portosystemic Shunt • Liver ... #diagnosis #treatment